Combined antimicrobial action of streptomycin and terpenes against atypical mycobacteria isolated from fish

Authors

  • L. Guz Department of Biology and Fish Diseases, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Akademicka 12, 20-033 Lublin, Poland
  • K. Puk Department of Biology and Fish Diseases, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Akademicka 12, 20-033 Lublin, Poland
  • D. Szwajgier Department of Biotechnology, Microbiology and Human Nutrition, University of Life Sciences in Lublin, Skromna 8, 20-704 Lublin, Poland
  • A. Pastuszka Department of Biology and Fish Diseases, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Akademicka 12, 20-033 Lublin, Poland

DOI:

https://doi.org/10.24425/pjvs.2024.149334

Abstract

The aim of this study was to investigate the antimycobacterial activity of 39 free terpenes and their activity in combination with streptomycin. Antimicrobial activity was first evaluated by screening 39 free terpenes at concentrations from 1.56 to 400 μg/mL. None of these exhibited positive effects against any of the nontuberculous mycobacteria (NTM) strains tested. However, six of the 39 terpenes (isoeugenol, nerol, (+)-α-terpineol, (1R)-(−)-myrtenol, (+)-terpinen-4-ol, and eugenol) were shown to enhance the activity of streptomycin against the NTM strains isolated from diseased ornamental fish.

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Published

2024-03-30

How to Cite

Guz, L., et al. “Combined Antimicrobial Action of Streptomycin and Terpenes Against Atypical Mycobacteria Isolated from Fish”. Polish Journal of Veterinary Sciences, vol. 27, no. 1, Mar. 2024, pp. 135-8, doi:10.24425/pjvs.2024.149334.

Issue

Vol. 27 No. 1 (2024)

Section

Article